How can SSRI’s cause dry mouth when they don’t affect the acetylcholine receptor?
January 22, 2012 - 9:02 pm
Some have a mild affinity. Citalopram has no effect on the receptor, yet like all ssri’s it lists dry mouth as a side effect, claiming 20% of users report it.
Seriously asking a psychopharmacology question on YA! is not going to elicit many answers, that said, I’d recommend reading the PI sheet that comes with the medication.
There are several types of 5-HT receptors, the potential for cholinergic over lay exists, and the mechanism of "dry mouth" isn’t necessarily solely the responsibility of ACH.
Other articles you might like;
January 23rd, 2012 at 2:15 am
Seriously asking a psychopharmacology question on YA! is not going to elicit many answers, that said, I’d recommend reading the PI sheet that comes with the medication.
There are several types of 5-HT receptors, the potential for cholinergic over lay exists, and the mechanism of "dry mouth" isn’t necessarily solely the responsibility of ACH.
References :